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All posts by Natural Foundations

What type of brain inflammation do you suffer from?

901 types of brain inflammation If you suffer from autoimmune Hashimoto’s low thyroid, you may also suffer from some degree of brain inflammation. Symptoms of brain inflammation brain fog, fatigue, poor motivation, and depression. Sometimes brain inflammation can be debilitating if it is advanced enough. What type of brain inflammation do you have? Brain inflammation can be subtle, moderate, or severe. It can also be transient or chronic. If you have autoimmune Hashimoto’s, you should also be mindful of brain autoimmunity, another factor in causing brain inflammation.

Subtle brain inflammation:

  • Brain fog
  • Slower mental speed
  • Lower brain endurance (can’t read, work, or drive as long you used to)
  • Brain fatigue after exposure to specific foods or chemicals
  • Comes and goes

Moderate brain inflammation:

  • Fatigue
  • Depression
  • Lack of motivation
  • Unable to focus and concentrate well
  • Always sleepy
  • Need to sleep more than 8 hours
  • Lethargy
  • Appetite loss
  • Unable to be physically active

Severe brain inflammation:

  • Disorientation or confusion
  • Dementia
  • Delirium
  • Coma
  • Seizures
  • Difficulty speaking
  • Tremors or trembling
  • Involuntary twitching

Transient neuroinflammation:

  • Exposure to a trigger activates symptoms but they subside. Individual has more good days than bad.

Chronic neuroinflammation:

  • Symptoms persistent chronically and the individual has more bad days than good.

Neurological autoimmunity

  • Autoimmunity is a condition in which the immune system attacks tissue in the body, mistaking it for a foreign invader. Hashimoto’s is caused by the immune system attacking the thyroid gland and neuroautoimmunity happens when the immune system attacks nerve tissue. This causes neurological symptoms, depending on the area of the brain being attacked. These individuals also suffer from the common symptoms of brain inflammation, such as brain fog, fatigue, and depression. If you have Hashimoto’s it’s important to rule out whether you have brain autoimmunity.

Why brain inflammation happens

We’re accustomed to thinking neurons are the primary cells in the brain, but they actually only make up about 10 percent of the brain. The rest of the brain is comprised of the brain’s immune cells, called glial cells. These cells outnumber neurons 10 to 1. Researchers have discovered glial cells do significantly more than protect the brain. When the brain is not engaged in inflammation, glial cells support healthy neuron function, remove plaque and debris that can lead to neurodegenerative diseases, and support healthy communication between neurons. Things that cause brain inflammation include brain injury, autoimmune disease, insulin resistance and diabetes, inflammatory foods, food intolerances, excess alcohol consumption, chronic viral or bacterial infections, leaky gut, leaky blood-brain barrier, hormonal imbalances, or other chronic imbalances. Chronic brain inflammation steals glial cells away from supporting neurons to instead engage in inflammatory combat. If your symptoms are mild, functional medicine protocols can help reverse them. As long as you follow a healthy diet and lifestyle, you can live a life largely free of brain inflammation symptoms. These protocols include:
  • Balancing blood sugar; lower high blood sugar.
  • Do not eat foods that cause an inflammatory reaction, particularly gluten.
  • Repair leaky gut and leaky blood-brain barrier.
  • Improving diversity of your gut microbiome.
  • Manage your Hashimoto’s low thyroid.
  • Manage chronic infections.
  • Taking glutathione and other supplements that dampen inflammation.
  • Exercise daily, particularly with high-intensity interval training (HIIT).
  • Balance your hormones.
If your brain inflammation is moderate to severe, you may need to go beyond these steps to pursue one or more root causes more emphatically. The brain’s immune system does not have an off switch like the body’s and brain inflammation can damage brain tissue for a long time. Also, a severe brain inflammatory event can cause glial cells to become “primed.” This means the cell’s shape has permanently changed so that it no longer can help neurons and just functions in an inflammatory capacity. These glial cells also die sooner. If your glial cells are primed, this means acute inflammatory triggers can set off severe brain inflammation symptoms, such as bouts of memory loss, inability to speak properly, loss of muscle function, being bedridden from fatigue, and more. Trigger-happy neurons Outside of brain inflammation another mechanism that can cause brain symptoms is called “neurons close to threshold.” This happens when neurons are too weak and fragile and are easily overwhelmed, which causes them to fatigue. Smelling perfumes for the chemically sensitive person, eating gluten for the gluten intolerant person, pushing your brain past what it can handle (with reading, working, studying, driving, etc.), too much noise for someone who is sound sensitive, etc. are examples of events that can fatigue weak neurons. This happens because poor habits or chronic inflammation damages the neurons’ mitochondria, the energy factory in each cell. This weakens the neurons and causes them to fire too easily and fatigue. This is a broad overview of neuroinflammatory concepts. Ask my office how we can help you manage your brain inflammation.
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Staying thin is harder for young people than in the past

If you feel like you have a harder time staying slim than your grandparents did at your age, you are right. We are about 10 percent heavier than people in the 80s, even when we eat the same foods and exercise just as much. This may be due to changes in lifestyle and environmental factors that impact our BMI, or body mass index.

Recent research by York University’s Faculty of Health shows it’s harder to maintain the same weight at a certain age than it was for someone 20 or 30 years ago. Even if you eat exactly the same macros (protein, fat, and carbs) and do the same amount and type of exercise, you are likely to be heavier than they were at your age.

In fact, with all factors accounted for, the predicted BMI has risen 2.3 points between 1988 and 2006.

According to study author Jennifer Kuk, “Our study results suggest that if you are 40 years old now, you’d have to eat even less and exercise more than if you were a 40-year-old in 1971, to prevent gaining weight. However, it also indicates there may be other specific changes contributing to the rise in obesity beyond just diet and exercise.”

Specific factors contribute to our increased BMI

Historically we tend to look only to dietary and exercise habits when we consider our weight or BMI (body mass index).

However, weight management is much more complex than watching what you eat and how much you work out. Our BMI is affected by many factors such as:

  • Medication use
  • Environmental toxins
  • Genetics
  • Meal timing
  • Stress level
  • Gut bacteria populations
  • Nighttime light exposure

While the study’s authors admit we need more research to determine exactly how these factors play into the changed BMI picture, they suggest three main players:

Increased environmental toxins. Compared to 30 years ago, we are exposed to a higher level of environmental toxins such as pesticides, air pollution, heavy metals, flame retardants, plastics used for food storage, and more. These toxins put a heavy burden on the endocrine system, altering the hormonal processes that affect metabolism and weight management.

Increased use of prescription drugs. Since the 1970s our use of prescription drugs has risen dramatically. Many antidepressant drugs are linked with weight gain and are the most prescribed drugs in the US for people between 18 and 44.

Our gut microbiome has changed. The gut microbiome, or the community of good and bad bacteria that naturally inhabit the digestive tract, have changed dramatically since the 80’s.

Americans eat differently than they used to. The products we eat are more filled with antibiotics, pesticides, and other toxins; we eat more artificial sweeteners; and we eat more junk food. All of these factors may negatively affect our gut bacteria populations.

A hot topic of research, the gut microbiome is linked to more and more aspects of health and disease. We now know that some gut bacteria are linked with weight gain and obesity. In fact, doctors are even using fecal implantation — insertion of gut bacteria from a healthy slim patient into the gut of an unhealthy obese patient — to reduce chronic obesity.

Support your microbiome with SCFA

In functional medicine we consider the gut microbiome to be a foundation of health. An imbalanced gut microbiome can prevent you from healing from many health disorders, so it makes sense to do everything you can to support yours.

One important factor is oral tolerance, or the body’s ability to properly recognize food proteins. When we lose oral tolerance, the immune system mistakenly thinks more and more foods are pathogens, and we begin to have more food sensitivities, increased hormonal issues, increased autoimmunity, and imbalanced metabolism and weigh gain.

You can support oral tolerance by fixing leaky gut, supporting liver function, taming histamine reactions, reducing stress, and balancing blood sugar. But one of the best ways to support it is by providing your body with plenty of short-chain fatty acids (SCFA).

SCFA are powerful gut signaling compounds found in fruits and vegetables that affect not only the gut but also the brain and other parts of the body.

Your gut bacteria not only make SCFA, they also need them as fuel to produce more SCFA. The more you eat them, the more your good gut bacteria can outweigh the bad.

Three main SCFAs include:

  • Butyrate
  • Propionate
  • Acetate

SCFA bind to cell receptors that control your hunger and appetite, turn off insulin resistance, and burn body fat more efficiently.

When you are low on SCFA you will:

  • Have a larger appetite
  • Be prone to insulin resistance (think pre-diabetes)
  • Store body fat better than you burn it

When gut diversity is ruined, SCFA can’t signal properly and you end up with what we call an “obese microbiome.”

How to support SCFA

To support healthy levels of SCFA, adopt the following habits:

Eat abundant and varied produce. Eat plenty of diverse vegetables so your gut bacteria stay adept at recognizing many different food proteins. Aim for 7 to 9 servings a day. One serving consists of a half cup of chopped vegetable or one cup of shredded greens. Go easy on high-sugar fruits to keep your blood sugar stable.

Supplement with SCFA. You may benefit from also supplementing with butyrate, the main SCFA. Start with one capsule a day and work your way up to two capsules twice a day.

Boost glutathione levels. Glutathione is the master antioxidant that helps dampen inflammation, a main factor in loss of microbiome diversity. Take absorbable glutathione such as s-acetyl glutathione (regular glutathione isn’t absorbed well), or its precursors such as n-acetyl cysteine.

There are many other helpful ways to support a healthy microbiome. Contact my office to determine your microbiome health and how to improve it, so you can maintain a healthy weight.

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Statins raise diabetes risk; what to do instead of drugs

You’ve been told you need to lower your cholesterol, but did you know taking a statin could raise your risk of type 2 diabetes? A recent study of almost 9,000 people in their 60s showed that statin use increased the risk of diabetes by almost 40 percent. Statin use was also associated with a higher risk for elevated blood sugar and insulin resistance (pre-diabetes). While the brand of statin subjects took didn’t seem to matter, risk was higher in overweight and obese subjects.

Given the risks associated with high blood sugar, insulin resistance, and diabetes, this study highlights further problems with statin use for a condition that is typically well managed through functional medicine protocols. High blood sugar and diabetes raise your risk for many chronic health disorders, including dementia and Alzheimer’s.

This isn’t the first study to link statins with an increased risk of type 2 diabetes. Previous research has found a 50 percent increased risk of diabetes in female users.

Statins most commonly prescribed drugs

Statins are among the most commonly prescribed drugs, accounting for more than $20 billion of spending a year. About one in four Americans over 40 takes statins, with that number having increased by almost 80 percent in the last two decades. Side effects include muscle weakness and wasting, headaches, difficulty sleeping, and dizziness.

Statins do not address the underlying cause of high cholesterol

Although statins lower cholesterol, they do not address the underlying cause of high cholesterol in most people, which is typically inflammation (some people have a genetic disorder that causes very high cholesterol). The body uses cholesterol to patch up damage in the arteries caused by inflammation. In fact, research shows inflammation is the primary cause of heart attacks and strokes, not high cholesterol.

Considering the following facts about cholesterol and heart disease:

  • 75 percent of peoplewho have heart attacks have normal cholesterol.
  • Older patientswith low cholesterol have a higher risk of death than those with higher cholesterol.
  • Populations in other countries with higher cholesterol than Americans have less heart disease.

Hypothyroidism, a condition estimated to affect more than 20 million Americans, raises cholesterol. Many find a gluten-free diet lowers cholesterol, as gluten is inflammatory for so many people.

Research also shows diets low in fat and high in carbohydrates increase the “bad” form of LDL (there are two to look at) and decrease the protective HDL.

Lowering cholesterol through functional medicine

Using functional medicine is a highly effective way to lower cholesterol naturally. This is because functional medicine identifies and manages the root cause of a problem versus using a drug to block symptoms.

Management includes an anti-inflammatory diet, exercise, nutritional support, and finding out causes of inflammation. These may include low thyroid function, autoimmune disease, bacterial or viral infections, leaky gut, poor blood-sugar handling, or other chronic health issues.

In fact, high cholesterol is more often tied to a diet too high processed carbohydrates and sugars, not fat. Sugar and refined carbs, including processed white foods, drive good cholesterol down and triglycerides up. It causes low density small particles that encourage the dangerous buildup of arterial plaque. This can lead to not only heart disease but also insulin resistance or “pre-diabetes.” Sugar, not dietary fat, is the bigger cause of most heart attacks.

However, the type of fat you eat matters too. Trans fats, or hydrogenated fats, promote dangerous types of cholesterol, while omega-3 fats and monounsaturated fats improve the healthy types of cholesterol.

Measuring cholesterol players

Cholesterol is found in every cell and helps produce cell membranes, vitamin D, and hormones. It’s also necessary for good neurological function.

When we measure cholesterol, we are measuring LDL and HDL. These are small packages of fat and protein that help move cholesterol throughout the body.

High-density lipoprotein — HDL

This is considered “good” cholesterol. It helps removes excess arterial plaque.

Low-density lipoprotein — LDL

This is considered “bad” cholesterol. It can form plaque that narrows the arteries and makes them less flexible (atherosclerosis).

Triglycerides

High levels of this dangerous fat are linked to heart disease and diabetes. Levels rise from eating too many sugars and processed carbs, as well as from smoking, physical inactivity, excessive drinking and being overweight.

Lipoprotein (a) or Lp(a)

Lp(a) is made up of an LDL part plus a protein (apoprotein a). Elevated Lp(a) levels are a strong risk for heart disease.

When testing cholesterol, please pay attention to:

  • Levels of HDL “good” cholesterol versus LDL “bad” cholesterol
  • Triglyceride levels
  • The ratio of triglycerides to HDL
  • The ratio of total cholesterol to HDL

Inflammation promotes heart disease

Systemic inflammation is a primary factor in heart disease and most chronic health disorders. A diet high in sugars and processed carbs, a sedentary lifestyle, smoking, excessive drinking, chronic stress, gut infections, unmanaged autoimmunity, and chronic infections are all causes of chronic inflammation. People with elevated systemic inflammation, which is measured by a blood marker called C-reactive protein (CRP) have a higher risk for heart disease than those with high cholesterol. Also, normal cholesterol is not protective for those with high CRP.

By addressing the cause of high cholesterol not only do you avoid the dangerous risks and unpleasant side effects of statins, but also you journey into your golden years with improved energy and well being.

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Is chronic stress damaging you? Take an adrenal test

Many of us are too stressed out these days and this can have negative consequences on our bodies and brains, promoting chronic disease and rapid brain degeneration. If you’re concerned about the effects of stress on your body and how to manage it, an adrenal salivary test is an important ally. It can show you whether your stress hormone cortisol is too high or too low and whether this has affected your sleep-wake cycle, or circadian rhythm.

Symptoms of low adrenal hormones

  • Fatigue
  • Slow starter in the mornings
  • Crash in the afternoon
  • Crave sweets, caffeine, or nicotine to keep going
  • Prone to moodiness
  • Become shaky, light-headed, or irritable if go too long without eating
  • Wake up at 3 or 4 a.m.; inability to stay asleep
  • Become dizzy when move from sitting to standing

Symptoms of high Adrenal hormones

  • Excess belly fat
  • Insulin resistance (high blood sugar)
  • Trouble falling asleep
  • Wake up not feeling rested
  • Women grow facial hair; men grow breasts
  • Polycystic ovarian syndrome (PCOS).

How to do an adrenal salivary test

To perform the adrenal salivary test, simply collect a small vial of saliva several times throughout the day using the vials in your test kit. The lab will then analyze your saliva for cortisol levels and how much cortisol you produce in the morning, afternoon, and evening. Do not do something unusual or stressful on the day of your test.

It’s important to understand that low or high adrenal hormones usually don’t reflect a problem solely with the adrenal glands, two glands that sit atop each kidney and secrete adrenal hormones. Instead, chronic stress affects stress pathways in the brain, which start to dysfunction when stress is chronic.

It isn’t just being too busy, a bad job, a bad relationship, and so forth that cause chronic stress. Lesser known factors of chronic stress can include unstable blood sugar (usually from too many carbs), a chronic infection, leaky gut, or an autoimmune disease. Using second and third adrenal salivary tests allow you to track whether you’re successfully managing your condition; adrenal health should improve as these conditions resolve. If adrenal health does not improve, it means you must keep investigating to find out what is causing the body stress.

Measuring the sleep-wake cycle, or circadian rhythm

A sleep-wake cycle, or circadian rhythm, that is out of whack is one symptom of adrenal stress. If the circadian rhythm is normal, then cortisol is highest in the morning and lowest at night. This is what allows us to feel alert when we wake up and sleepy before bed. Many people with altered circadian rhythms notice they are more awake at night. Or they may notice an energy crash in the afternoon and being wide awake in the middle of the night.

The stages of stress

The adrenal salivary test measures circadian rhythm, the cortisol precursor hormones DHEA and 17 hydroxyprogesterone, and cortisol levels. It can tell you where you fall on the spectrum of adrenal fatigue to high adrenal hormones.  People don’t necessarily progress from high adrenal hormone to low; adrenal function can jump back and forth between phases or stay stuck in one phase.

The adrenal salivary test also measures total secretory Ig antibodies, or (SIgA). Low SIgA levels reflect poor and dysfunctional immunity. If your SIgA levels are low, you are more prone to food intolerances, chemical sensitivities, autoimmune disease, infections, and other assaults on the immune system.

Ask my office about functional medicine protocols that can profoundly influence your adrenal health. We will also search for and manage the root causes of your adrenal stress.

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Six Lifelong Habits Found Among The Happiest People

In functional medicine we look at diet and lifestyle strategies to prevent or reverse disease, calm inflammation, and slow the aging process. However, other overlooked but extremely important aspects to your health are your general happiness, well-being, and attitude. Science shows happiness and positivity are correlated with better health. If you are not naturally happy, not to worry, simply putting forth small and regular efforts in the direction of happiness, such as writing in a gratitude journal, has been shown to improve health.

In what is thus far the most comprehensive study on what makes people happy, researchers looked at the lives of Harvard graduates, blue collar workers, and women spanning almost a decade. From that data, they found six common themes that ran through the lives of the happiest lifelong subjects.

 

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New food sensititivies? Look at loss of oral tolerance

If you have an autoimmune condition, you may be familiar with restricted diets such as the autoimmune protocol (AIP), GAPs, or FODMAPs. These diets can significantly reduce inflammation, help you determine food sensitivities, and address root causes of mysterious symptoms. However, some people experience little to no improvement and may even get new food sensitivities. The culprit could be loss of oral tolerance.

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NSAIDs — the dangers and the alternatives for pain

According to the National Institutes of Health, nearly 50 million American adults have chronic pain or severe pain. The conventional medical model teaches us to reach first for medication to relieve pain, with ibuprofen and other NSAIDs (nonsteroidal anti-inflammatory drugs) at the top of the list. However, with research mounting to show NSAIDs have a notable list of dangers, it makes sense instead to look for the root causes of pain. 

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Chronic Viruses Linked to Inflammatory Diseases

Viral Infections | Chiropractors CapitolaThe Epstein-Barr virus infects more than 90 percent of people in the United States by the age of 20. At least one in four of those infected will develop

the commonly-known disease mononucleosis, or “mono,” experiencing a rash, enlarged liver or spleen, head- and body aches, and extreme fatigue.

However, Epstein-Barr virus (EBV) is not only related to mono. Recent studies indicate it may be a catalyst for at least six more diseases, most of which are autoimmune in nature. These include multiple sclerosis, inflammatory bowel disease, rheumatoid arthritis, celiac disease, Type 1 diabetes, and juvenile idiopathic arthritis.

 

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Antacid and Antibiotics Raise Allergy Risk in Children

Addressing the root cause of your child’s acid reflux or frequent illnesses instead of a pharmaceutical quick fix could save you both bigger headaches down the road. A large study shows antacid and antibiotic use in early childhood significantly raises the risk of developing allergiesAddressing the root cause of your child’s acid reflux or frequent illnesses instead of a pharmaceutical quick fix could save you both bigger headaches down the road. A large study shows antacid and antibiotic use in early childhood significantly raises the risk of developing allergies.

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Want to trash your lungs? Use basic cleaning products.

Smoking is bad for you and cleaning house is good, right? Wrong. If you use conventional cleaning products, you may as well smoke. A new study shows the lung decline over 20 years caused by using conventional cleaning products, which have no federal regulations for health or safety, equals that of smoking 20 cigarettes a day. The toxic chemicals used in cleaning products damage the lungs little by little, adding up to a significant impact that rivals a pack-a-day smoking habit. 

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